Neuronal aging and its implications in human neurological pathology
İÇİNDEKİLERCONTENTS 1. Introduction 2. Basic aspects of neuronal aging 2.1 Morphology ............ 2.2 Pathophysiology......... 2.3 Biochemistry............ 3. Immunological and viral aspects of neuronal aging ....................... 3.1 Heterogenic autoantibody directed against axonal neurofilaments in SSVE, Alzheimer disease, and other chronic CNS diseases ............ 3.2 Strain differences among SSVE viruses ............................. 4. Social, behavioural, and psychological factors in neuronal aging............ 4.1 Social .......................................................... 4.2 Psychological ................................................... 4.3 Suicide ......................................................... 4.4 Prevention...................................................... 5. Clinical aspects of neuronal aging...................................... 5.1 Prevalence and mortality ......................................... 5.2 Clinical aspects and diagnosis ..................................... 5.3 Diagnostic perspectives........................................... 5.4 Therapeutic perspectives ......................................... 5.5 The brain in dementia and aging................................... 6. Techniques for studying the brain in vivo ............................... 6.1 Oxidative metabolism of intact brain ............................... 6.2 Imaging of the brain in vivo and its role, present and future, in dementia ....................................................... 7. Models for the study of pathological neuronal aging...................... 7.1 Morphological markers of Alzheimer disease ........................ 7.2 Experimental models produced by the injection of very small quantities of an unconventional agent into the brain ...................... 8. Pharmacological control of neuronal aging .............................. 9. Neurosurgical treatment of age-related neurological disorders ............. 10. Conclusions and recommendations..................................... References ............................................................. |