Developments in Malaria Immunology
İÇİNDEKİLERCONTENTS Introduction 1.Mechanisms of malaria resistance................. 1.1. Life cycle and pathogenesis.................. 1.2 Mechanisms of innate resistance ............... 1.3 Antibody responses and antibody effector mechanisms in immunit to malaria......................... 1.4 Cell-mediated responses and effector mechanisms....... . 1.5 Mechanisms of survival of malaria parasites in the immunized host References......................... 2. Serology of malaria .................. 2.1 Antigens in malaria serology............ 2.2 Tests in common use for detection of malarial antibodies 2.3 Serology as an aid to diagnosis........... 2.4 Recommendations................. References.................... 3. Immunopathology of malaria....... 3.1 Introduction............ 3.2 Immune complexes in malaria . . . . 3.3 Complement changes in malaria 3.4 Renal lesions in malaria....... 3.5 Anaemia in malaria......... 3.6 Cerebral malaria.......... 3.7 Tropical splenomegaly syndrome(TSS) 3.8 Autoimmunity in malaria 3.9 Immunosuppressive effects of malaria . 3.10 Other immunopathological effects . . . References............. 4. Immunization against malaria................... 4.1 Immunization with parasitized erythrocytes or parasite fractions . 4.2 Immunization with merozoites................ 4.3 Immunization with sporozoites................ 4.4 Immunization with exoerythrocytic merozoites of avian malaria . . 4.5 Comparative assessment of experimental methods of immunization References......................... 5. The cultivation of malarial parasites in vitro 5.1 Axenic culture.......... 5.2 The sporogonic cycle....... 5.3 The exoerythrocytic cycle ..... 5.4 The erythrocytic cycle....... 5.5 Recommendations......... References............  |
