Comparative Studies of American Trypanosomiasis
İÇİNDEKİLERCONTENTS Introduction 1. General considerations.................... 2. Morphological and biological variations between species and strains 2.1 Morphology 2.2 infrastructure . . 2.3 Immunology................... 2.4 Hosts...................... 2.5 Comparative physiology, metabolism, and biochemistry 2.6 Trypanosome polymorphism............ 3. Immunology........................ 3.1 Immunopathology................... 3.2 Immunodiagnosis.................... 3.3 Characteristics of antigens................ 3.4 Serolpgical tests in the host............... 3.5 Application of tests in diagnosis............. 3.6 Preparation of antigens................. 3.7 Active immunization with dead and living vaccines..... 4. Epidemiology........................ 4.1 Reservoir hosts..................... 4.2 Man-vector contact and its effects............. 4.3 Epidemiological effects of the environment........ 5. Clinicopathological aspects.................. 5.1 Distribution of trypanosomes in host tissues........ 5.2 Site-of-entry lesions................... 5.3 Cardiac lesions..................... 5.4 Neurological lesions................... 5.5 Clinical manifestations caused by different species and strains 5.6 Congenital trypanosomiasis............... 5.7 The role of antigen-antibody reactions in pathogenesis . . . 6. Chemotherapeutic problems.................. 6.1 Mechanism of drug action................ 6.2 Future development of chemotherapy........... 6.3 Drug resistance..................... 7. Methods................. 7.1 Measurement of infectivity and virulence. 7.2 Maintenance of trypanosomes..... 8. Recommendations for research....... 9. General recommendations.........  |
