Scandinavian Journal of Work, Environment & Health

Book : Scandinavian Journal of Work, Environment & Health

Author : * --

Language : English

Episode : Health-Safety-Environment

Publishing Location : Danimarka

ISSN : 0355-3140

Skin : 24-1

Period : bimonthly

Published Date : 1998

Publisher : Finnish Institute of Occupational Health

Document Type : Periodical

Book No : 1402

INDEX

CONTENTS - Supplement 1,1998
Preface
Dedication to Professor Emeritus Lars Friberg
Abbreviations
Conclusions
7 Summary
8 Introduction
9 Exposure and dose
9 Occupational exposure
9 Environmental exposure
9 Exposure to cadmium in air
9 Smoking
9 Drinking water
10 Dietary intake
11 Biological indicators of exposure and dose
11 Cadmium kinetics
11 Cadmium in blood
13 Urinary cadmium
14 Cadmium in kidneys
14 Cadmium in placenta
15 Trends in human cadmium exposure
15 Cadmium in crops or wheat
15 Dietary intake of cadmium
16 Blood and urinary cadmium levels
16 Cadmium in kidneys
16 Cadmium in human bone tissue
16 Concluding remarks
17 Risk groups and risk factors for high exposure or dose
17 Environmental exposure
17 Smoking
17 Dietary habits
17 Nutritional factors
18 Women
18 Kidneys
18 Environmental exposure and the kidneys
19 .. Normal kidney function and the early diagnosis
of damage from toxic substances
19 Normal function of the kidneys
19 Different types of renal damage
19 Early diagnosis of renal damage and
impairment of renal function
20 Cadmium exposure and the kidneys
20 Tubular damage
21 Glomerular damage
21 Kidney stones
22 Vitamin D
22 Dose-response relationship for the development
of renal effects and prognosis
22 Environmental exposure to cadmium and renal
effects
22 Dose-response analysis
24 Long-term prognosis
(Contents continues on page 52 of the supplement)

CONTENTS
(continued from back cover)
25 Occupational exposure to cadmium and renal effects
25 Dose-response analysis
26 Long-term prognosis
26 Overall evaluation of the risk for renal toxicity from cadmium exposure
28 Mechanisms related to the expression of kidney effect
28 Toxicokinetic aspects on transport of cadmium to the kidney
29 Cellular targets for the cadmium role of membrane damage and protective
cadmium-binding proteins
30 Influence of zinc and copper on cadmium nephrotoxicity
30 Cadmium-induced renal tubular damage - increased sensitivity in diabetics
30 Diabetes induced in animals by the injection of streptozotocin
31 Other animal models for diabetes
31 Bone
32 Effects in humans
32 Environmental exposure
33 Increased susceptibility to cadmium-induced bone injury in women
33 Occupational exposure
33 Effects in animals
34 Increased vulnerability to cadmium-induced bone injury among female animals
34 Cancer
34 Lung cancer
34 Human evidence
35 Animal evidence
35 Prostate cancer
35 Human evidence
35 Animal evidence
36 Renal cancer
36 Breast cancer
36 Other cancers
36 Concluding remarks
37 Cardiovascular system
37 Reproductive and developmental effects
37 Male reproductive system
37 Effects on humans
38 Effects on experimental animals
38 Female reproductive system
38 Effects on humans
39 Effects on animals
39 Embryotoxic, teratogenic and developmental effects - animals
40 Summary and concluding remarks
40 Male reproductive system
40 Female reproductive system, teratogenic and developmental effect
41 Risk characterization
43 Discussion of the risk characterization
44 Acknowledgments
44 References