Scandinavian Journal of Work, Environment & Health

Book : Scandinavian Journal of Work, Environment & Health

Author : * --

Language : English

Episode : Health-Safety-Environment

Publishing Location : Sweden

ISSN : 0355-3140

Skin : 3-1

Period : bimonthly

Published Date : 1977

Publisher : Finnish Institute of Occupational Health

Document Type : Periodical

Book No : 1342

INDEX

CONTENTS
Introduction
General background
PULMONARY EFFECTS AFTER EXPOSURE TO MANGANESE DIOXIDE Epidemiologic studies
Experimental studies
CONCLUSIONS AND COMMENTS
SCOPE OF THE PRESENT INVESTIGATION
Material and methods
EXPERIMENTAL TECHNIQUES
Animals
Manganese dioxide aerosol
Generation
Particle size and dust concentration
Exposure conditions
Bacterial aerosol
Exposure regimes
Preparations and measurements
Determination of manganese dioxide in the lung
Number of free lung cells
Determination of macrophages with phagocytized manganese dioxide
particles
Measurement of clearance of viable bacteria
Histological evaluation of lung section
TREATMENT OF DATA
Results
LUNG CLEARANCE OF MANGANESE DIOXIDE PARTICLES
NUMBER OF MACROPHAGES
NUMBER OF LEUKOCYTES
PHAGOCYTOSIS OF MANGANESE DIOXIDE
CLEARANCE OF VIABLE BACTERIA
CHANGES IN LUNG TISSUE AFTER EXPOSURE TO MANGANESE DIOXIDE
General discussion
METHODS
RESULTS
Lung clearance
Macrophages
Leukocytes
Clearance of viable bacteria Histology
Conclusions
Summary
Acknowledgments References
Appendix